백서 두개골에 형성된 골 결손부 크기에 따른 골 치유과정에 대한 조직학적 연구
HISTOLOGIC STUDY OF HEALING PROCESS OF DEFFERENT SIZE CALVARIAL DEFECTS IN RATS
단국대치의학연구소논문집 1994년 6권 1호 p.57 ~ 65
소속 상세정보
윤도철/Yun, Do-Cheol
김경욱/임창준/김종여/Kim, Kyung-Wook/Yim, Chang-Joon/Kim, Jong-Yeo
KMID : 0354619940060010057
Abstract
The author made calvarial defects of different sizes in rat to study the effect of defect size on hea1ing process. Experimental animals were sacrified at 3 days, 1 week, 2,4,6 weeks. The specimens were examed under light microscope with Hematoxlin-Eosin and modified Gomlori´s trichrome stain, and under fluorescent microscope after glinding the specimens.
The results were as follows.
1. 4mm-diameter calvarial defects healed about 70% after 6 weeks.
2. Lamellated bone tralbecules were seen in 6mm-diameter calvarial defects after 4 weeks, and the small specules of bone and marrows were observed after 6 weeks.
3. 10mm-diameters calvarial defects healed about 50% and incomplete interconnection of the lamellated bone trabecules were observed after 6 weeks.
4. Under fluorescent microscope, about 4mm-long bone regeneration could be seen in most of the defects.
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